IL22RA2 Protein (His tag)
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- Target Alle IL22RA2 Proteine anzeigen
- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL22RA2 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Active Recombinant Human IL-22RA2/IL22BP Protein
- Sequenz
- TQSTHESLKP QRVQFQSRNF HNILQWQPGR ALTGNSSVYF VQYKIYGQRQ WKNKEDCWGT QELSCDLTSE TSDIQEPYYG RVRAASAGSY SEWSMTPRFT PWWETKIDPP VMNITQVNGS LLVILHAPNL PYRYQKEKNV SIEDYYELLY RVFIINNSLE KEQKVYEGAH RAVEIEALTP HSSYCVVAEI YQPMLDRRSQ RSEERCVEIP
- Spezifität
- Thr22-Pro231
- Reinheit
- > 90 % by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant Human IL22 at 2 μg/mL (100 μL/well) can bind recombinant Human IL22BP, the EC50 of Human IL22BP is 10.78 ng/mL.
- Top Product
- Discover our top product IL22RA2 Protein
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Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-231) protein (His tag)
IL22RA2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-263) protein (His tag)Crystallography grade IL22RA2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 21-230) protein (His tag)Crystallography grade IL22RA2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
- Andere Bezeichnung
- IL-22RA2/IL22BP (IL22RA2 Produkte)
- Synonyme
- CRF2-10 Protein, CRF2-S1 Protein, CRF2X Protein, IL-22BP Protein, IL-22R-alpha-2 Protein, IL-22RA2 Protein, ZCYTOR16 Protein, CRF2-s1 Protein, Il-22bp Protein, Crf2-s1 Protein, interleukin 22 receptor subunit alpha 2 Protein, interleukin 22 receptor, alpha 2 Protein, IL22RA2 Protein, Il22ra2 Protein
- Hintergrund
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Description: Interleukin 22 binding protein (IL-22BP), also known as CRF2-10, CRF2-X, and IL-22RA2, is a 35-45 kDa secreted glycoprotein in the type II cytokine receptor family (CRF). IL-22BP specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor.IL-22BP is produced by dendritic cells (DC), epithelial cells, activated B cells, and activated monocytes. It is constitutively expressed by DC but is down-regulated during local inflammation and in response to tissue damage. IL-22BP is critical for limiting IL-22 induced epithelial cell proliferation during wound healing, and its deficiency can enable uncontrolled proliferation and enhance tumor development.
Name: IL22RA2,CRF2-10,CRF2-S1,CRF2X,IL-22BP,IL-22R-alpha-2,IL-22RA2,ZCYTOR16
- Gen-ID
- 116379
- UniProt
- Q969J5-2
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