HPGD Protein (His tag)
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- Target Alle HPGD Proteine anzeigen
- HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses HPGD Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human 15-PGDH Protein (His Tag)
- Sequenz
- Met 1-Gln266
- Produktmerkmale
- Recombinant Human 15-Hydroxyprostaglandin Dehydrogenase [NAD(+)]/HPGD is produced by our Mammalian expression system and the target gene encoding Met1-Gln266 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HPGD Protein
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Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-266) protein (GST tag)
HPGD Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (Active) protein (His tag)HPGD Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE. Active
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-266) protein (His tag)HPGD Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-269) protein (Strep Tag)Crystallography grade HPGD Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-269) protein (His tag)HPGD Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HPGD Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES,150 mM NaCl, pH 7.4.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
- Andere Bezeichnung
- 15-PGDH (HPGD Produkte)
- Synonyme
- CBR Protein, SDR21C1 Protein, hCBR1 Protein, 15-PGDH Protein, PGDH Protein, PGDH1 Protein, PHOAR1 Protein, SDR36C1 Protein, MGC80546 Protein, MGC79454 Protein, AV026552 Protein, carbonyl reductase 1 Protein, 15-hydroxyprostaglandin dehydrogenase Protein, hydroxyprostaglandin dehydrogenase 15-(NAD) Protein, 15-hydroxyprostaglandin dehydrogenase L homeolog Protein, hydroxyprostaglandin dehydrogenase 15 (NAD) Protein, CBR1 Protein, HPGD Protein, hpgd.L Protein, hpgd Protein, pgdh Protein, Hpgd Protein, PTRG_03214 Protein, VDBG_09957 Protein
- Hintergrund
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Background: 15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
Synonym: 15-Hydroxyprostaglandin Dehydrogenase [NAD(+)], 15-PGDH, Prostaglandin Dehydrogenase 1, HPGD, PGDH1,PGDH,PHOAR1,SDR36C1
- Molekulargewicht
- 30.0 kDa
- NCBI Accession
- NP_000851
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