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HPGD Protein (AA 1-269) (His tag)
HPGD
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % by SDS - PAGE
SDS
Produktnummer ABIN5854804
Produktdetails
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Target
Alle HPGD Proteine anzeigen
HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-269
Spezies
Alle Spezies für HPGD Proteine
Human
Quelle
Alle Expressionssysteme für HPGD Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses HPGD Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK DQIKAMMKFY GVLHPSTIAN GLINLIEDDA LNGAIMKITA SKGIHFQDYD ISPLLVKAPL TS
Reinheit
> 95 % by SDS - PAGE
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl ( pH 8.0) containing 30 % glycerol
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Andere Bezeichnung
Hpgd (HPGD Produkte )
Synonyme
CBR Protein, SDR21C1 Protein, hCBR1 Protein, 15-PGDH Protein, PGDH Protein, PGDH1 Protein, PHOAR1 Protein, SDR36C1 Protein, MGC80546 Protein, MGC79454 Protein, AV026552 Protein, carbonyl reductase 1 Protein, 15-hydroxyprostaglandin dehydrogenase Protein, hydroxyprostaglandin dehydrogenase 15-(NAD) Protein, 15-hydroxyprostaglandin dehydrogenase L homeolog Protein, hydroxyprostaglandin dehydrogenase 15 (NAD) Protein, CBR1 Protein, HPGD Protein, hpgd.L Protein, hpgd Protein, pgdh Protein, Hpgd Protein, PTRG_03214 Protein, VDBG_09957 Protein
Hintergrund
Hpgd, also known as Hydroxyprostaglandin dehydrogenase, is a member of the short-chain dehydrogenases/reductases family. It metabolizes prostaglandins (PGs) to render them. Prostaglandins (PGs) play a crucial role in mediating parturition events, and their synthesis and metabolism are regulated by PGH synthase and 15-hydroxy-PG dehydrogenase (PGDH), respectively. Hpgd, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Recombinant mouse Hpgd protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molekulargewicht
31.6kDa (292aa)
NCBI Accession
NP_032304
UniProt
Q8VCC1
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