ENPEP Protein (His tag)

Produktnummer ABIN7195940

Produktdetails

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses ENPEP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse ENPEP/Aminopeptidase A Protein (His Tag)(Active)

Sequenz: Arg41-Pro945

Produktmerkmale: A DNA sequence encoding the mature form of mouse ENPEP (P16406) (Arg41-Pro945) was expressed, with a polyhistidine tag at the N-terminus.

Reinheit: > 91 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measured by its ability to cleave the fluorogenic peptide substrate, Glu-7-amido-4-methyl coumarin.The specific activity is > 200 pmoles/min/μg.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Andere Bezeichnung: ENPEP/Aminopeptidase A (ENPEP Produkte)

Synonyme: im:7152184 Protein, si:ch211-146m5.2 Protein, 6030431M22Rik Protein, APA Protein, Bp-1/6C3 Protein, Ly-51 Protein, Ly51 Protein, CD249 Protein, gp160 Protein, glutamyl aminopeptidase Protein, ENPEP Protein, enpep Protein, ECU01_1470 Protein, pepA Protein, LOC5568916 Protein, CpipJ_CPIJ011103 Protein, Eint_011390 Protein, Halhy_0222 Protein, Enpep Protein

Hintergrund:

Background: ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family. Members of this family are involved in response to cadmium ion and proteolysis. They located in 6 components and are expressed in 26 plant structures. ENPEP is expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. It also can be detected in a variety of other tissues. ENPEP probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. ENPEP is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.

Synonym: 6030431M22Rik,APA,Bp-1/6C3,ENPEP,Ly-51,Ly51

Molekulargewicht: 106 kDa

UniProt: P16406

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones