Galectin 3 Protein (LGALS3) (His tag)

Produktnummer ABIN7320933

Produktdetails

Target: Galectin 3 (LGALS3)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Galectin 3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Galectin-3/Lgals3 protein (His Tag)

Sequenz: 2A-264I

Produktmerkmale: A DNA sequence encoding the Mouse Galectin-3/Lgals3 protein (P16110) (2A-264I) was expressed with a polyhistidine tag at the N-terminus.

Reinheit: >90 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Immunogen(E-AB-40350)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3/Lgals3 (LGALS3 Produkte)

Synonyme: CBP 35 Protein, Gal-3 Protein, Galectin-3 Protein, leg3 Protein, galactoside-binding Protein, galectin-3 Protein, lectin Protein, soluble Protein, CBP35 Protein, GAL3 Protein, GALBP Protein, GALIG Protein, L31 Protein, LGALS2 Protein, MAC2 Protein, MGC52947 Protein, MGC75803 Protein, LGALS3 Protein, gal-3 Protein, GBP Protein, L-34 Protein, Mac-2 Protein, gal3 Protein, galectin 3 Protein, Galectin-3 Protein, avian beta-defensin 3 Protein, lectin, galactoside-binding, soluble, 3 L homeolog Protein, lectin, galactoside-binding, soluble, 3 Protein, galectin 2 Protein, lectin, galactose binding, soluble 3 Protein, LGALS3 Protein, leg3 Protein, AvBD3 Protein, lgals3.L Protein, lgals3 Protein, LGALS2 Protein, Lgals3 Protein

Substanzklasse: Chemical

Hintergrund:

Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Synonym: 35 kDa lectin,Carbohydrate binding protein 35,CBP35,GAL3,GALBP,GALIG,GBP,Gal-3,IgE binding protein,LGALS2,Macrophage galactose-specific lectin,Lectin L-29,Mac-2 antigen

Molekulargewicht: 27.4kDa

UniProt: P16110

Pathways: RTK Signalweg