FTL Protein (His tag)

Produktnummer ABIN7319279

Produktdetails

Target: FTL (Ferritin, Light Polypeptide (FTL))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FTL Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FTL Protein (His Tag)

Sequenz: Met 1-Asp175

Produktmerkmale: Recombinant Human Ferritin light chain is produced by our E.coli expression system and the target gene encoding Met1-Asp175 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,250 mM NaCl,1 mM EDTA, pH 9.5.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: FTL (FTL Produkte)

Synonyme: NBIA3 Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, FT Protein, Ftl Protein, Ftl-1 Protein, L-ferritin Protein, FTL Protein, Ftl1 Protein, FTL2 Protein, FTD Protein, ferritin light chain Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin light polypeptide 1 Protein, ferritin, light polypeptide Protein, ferritin light-chain Protein, ferritin light chain 1 Protein, FTL Protein, fth1.L Protein, Ftl1 Protein, CpipJ_CPIJ004069 Protein, Ftl Protein

Hintergrund:

Background: Ferritin is a large, iron-storage heteropolymeric protein,which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin has oligomer of 24 subunits and two types of subunits including light chain(FTL) and heavy chain. Ferritin can remove Fe (II) from solution in the presence of oxygen and is very important for iron homeostasis. Iron is absorbed in the ferrous form and deposited as ferric hydroxides after oxidation. Iron is first oxidized to the ferric state for storage as ferric oxyhdroxide whithin the protein shell of ferritin. Thus, ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. Ferritin also plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney.

Synonym: Ferritin L subunit,Ferritin light chain, FTL

Molekulargewicht: 24.5 kDa

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis