FTL Protein (AA 1-175) (His tag)

Produktnummer ABIN2115453

Produktdetails

Target: FTL (Ferritin, Light Polypeptide (FTL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-175

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FTL Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Ferritin Light Chain/FTL (N-6His)

Sequenz: MNHKVHHHHH HMSSQIRQNY STDVEAAVNS LVNLYLQASY TYLSLGFYFD RDDVALEGVS HFFRELAEEK REGYERLLKM QNQRGGRALF QDIKKPAEDE WGKTPDAMKA AMALEKKLNQ ALLDLHALGS ARTDPHLCDF LETHFLDEEV KLIKKMGDHL TNLHRLGGPE AGLGEYLFER LTLKHD

Produktmerkmale: Recombinant Human FTL is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp175) of Human FTL fused with a polyhistidine tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: Ferritin Light Chain (FTL Produkte)

Synonyme: NBIA3 Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, FT Protein, Ftl Protein, Ftl-1 Protein, L-ferritin Protein, FTL Protein, Ftl1 Protein, FTL2 Protein, FTD Protein, ferritin light chain Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin light polypeptide 1 Protein, ferritin, light polypeptide Protein, ferritin light-chain Protein, ferritin light chain 1 Protein, FTL Protein, fth1.L Protein, Ftl1 Protein, CpipJ_CPIJ004069 Protein, Ftl Protein

Hintergrund: Ferritin is a large, iron-storage heteropolymeric protein,which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin has oligomer of 24 subunits and two types of subunits including light chain(FTL) and heavy chain. Ferritin can remove Fe (II) from solution in the presence of oxygen and is very important for iron homeostasis. Iron is absorbed in the ferrous form and deposited as ferric hydroxides after oxidation. Iron is first oxidized to the ferric state for storage as ferric oxyhdroxide whithin the protein shell of ferritin. Thus, ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. Ferritin also plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney.
Synonyms: Ferritin L subunit,Ferritin light chain, FTL

Molekulargewicht: 24.5 kDa

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis