Ephrin A5 Protein (EFNA5) (His tag)

Produktnummer ABIN7320515

Produktdetails

Target: Ephrin A5 (EFNA5)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Ephrin A5 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Ephrin-A5/EFNA5 Protein (His Tag)(Active)

Sequenz: Gln21-Gln206

Produktmerkmale: Recombinant Mouse Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Gln206 is expressed with a 6His tag at the C-terminus.

Reinheit: > 90 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human EphA8-Fc(Cat: PKSH032386) at 1.5μg/ml(100 μl/well) can bind Human EFNA5-His. The ED50 of EFNA5-His is 12.63ug/ml .

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Ephrin A5 (EFNA5)

Andere Bezeichnung: Ephrin-A5/EFNA5 (EFNA5 Produkte)

Synonyme: EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein

Hintergrund:

Background: Ephrin-A5 is a glycosylphosphatidylinositol (GPI)-anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

Synonym: Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, Epl7, Eplg7, Lerk7, Efna5,

Molekulargewicht: 22.5 kDa

UniProt: O08543

Pathways: RTK Signalweg