EFNA4 Protein (His tag,Fc Tag)

Produktnummer ABIN7318438

Produktdetails

Target: EFNA4 (Ephrin A4 (EFNA4))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses EFNA4 Protein ist gelabelt mit His tag,Fc Tag.

Verwendungszweck: Recombinant Human Ephrin-A4/EFNA4 Protein (Fc & His Tag)(Active)

Sequenz: Leu26-Gly171

Produktmerkmale: Recombinant Human Ephrin-A4 is produced by our Mammalian expression system and the target gene encoding Leu26-Gly171 is expressed with a Fc, 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human EphA7-His(Cat: PKSH033689) at 2μg/ml(100 μl/well) can bind Human EFNA4-Fc-6His. The ED50 of Human EFNA4-Fc-6His is 1.5190 ug/ml .

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: EFNA4 (Ephrin A4 (EFNA4))

Andere Bezeichnung: Ephrin-A4/EFNA4 (EFNA4 Produkte)

Synonyme: EFNA4 Protein, EFL-4 Protein, Epl4 Protein, LERK-4 Protein, EFL4 Protein, EPLG4 Protein, LERK4 Protein, ephrin A4 Protein, ephrin-A4 L homeolog Protein, ephrin-A4 Protein, EFNA4 Protein, efna4.L Protein, efna4 Protein, Efna4 Protein

Hintergrund:

Background: Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. Ephrin-A4 consists of approximately 125 amino acids and includes four invariant cysteines, It has been shown to bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. Ephrin-A4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. It may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

Synonym: Ephrin-A4, EPH-Related Receptor Tyrosine Kinase Ligand 4, LERK-4, EFNA4, EPLG4, LERK4

Molekulargewicht: 44.3 kDa

UniProt: P52798

Pathways: RTK Signalweg