EDIL3 Protein (His tag)

Produktnummer ABIN7318421

Produktdetails

Target: EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses EDIL3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human EDIL3/Del-1 Protein (His Tag)

Sequenz: Val17-Glu480

Produktmerkmale: Recombinant Human EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 is produced by our Mammalian expression system and the target gene encoding Val17-Glu480 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))

Andere Bezeichnung: EDIL3/Del-1 (DEL1 Produkte)

Synonyme: si:dkey-84i7.1 Protein, Del1 Protein, XDel1 Protein, DEL1 Protein, Del-1 Protein, EGF-like repeats and discoidin I-like domains 3a Protein, EGF like repeats and discoidin domains 3 L homeolog Protein, EGF like repeats and discoidin domains 3 Protein, EGF-like repeats and discoidin I-like domains 3 Protein, edil3a Protein, edil3.L Protein, EDIL3 Protein, Edil3 Protein

Hintergrund:

Background: EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion. Human EDIL3 is synthesized as a precursor with a 16 amino acid signal sequence and a 464 amino acid mature chain.

Synonym: EGF-Like Repeats and Discoidin I-Like Domains 3, EDIL3

Molekulargewicht: 53.1 kDa

UniProt: Q8N610