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Complement Factor B Protein (CFB) (His tag)

CFB Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318328
  • Target Alle Complement Factor B (CFB) Proteine anzeigen
    Complement Factor B (CFB)
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 6
    • 4
    • 1
    Human
    Quelle
    • 14
    • 6
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Complement Factor B Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Complement Factor B/CFB Protein (His Tag)
    Sequenz
    Thr 26-Leu764
    Produktmerkmale
    Recombinant Human Complement Factor B is produced by our Mammalian expression system and the target gene encoding Thr26-Leu764 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CFB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Complement Factor B (CFB)
    Andere Bezeichnung
    Complement Factor B/CFB (CFB Produkte)
    Synonyme
    AHUS4 Protein, BF Protein, BFD Protein, CFAB Protein, FB Protein, FBI12 Protein, GBG Protein, H2-Bf Protein, PBF2 Protein, bf Protein, Bf-1 Protein, Brre-Bf Protein, zgc:114032 Protein, Bf Protein, Sp152 Protein, bfb-A Protein, Bf B Protein, LOC397725 Protein, bf/c2 Protein, CFB Protein, AI195813 Protein, AI255840 Protein, B Protein, C2 Protein, Fb Protein, Da1-24 Protein, complement factor B Protein, complement factor B S homeolog Protein, complement factor B L homeolog Protein, CFB Protein, cfb Protein, bf Protein, cfb.S Protein, cfb.L Protein, bf/c2 Protein, LOC100555981 Protein, Cfb Protein
    Hintergrund

    Background: Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

    Synonym: Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD

    Molekulargewicht
    84.1 kDa
    UniProt
    P00751
    Pathways
    Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
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