CTHRC1 Protein (His tag)

Produktnummer ABIN7318344

Produktdetails

Target: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CTHRC1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CTHRC1 Protein (His Tag)

Sequenz: Ser31-Lys243

Produktmerkmale: Recombinant Human Collagen triple helix repeat-containing protein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Lys243 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Andere Bezeichnung: CTHRC1 (CTHRC1 Produkte)

Synonyme: CTHRC1 Protein, cthrc1 Protein, zgc:101075 Protein, 1110014B07Rik Protein, collagen triple helix repeat containing 1 Protein, collagen triple helix repeat containing 1a Protein, CTHRC1 Protein, cthrc1 Protein, cthrc1a Protein, Cthrc1 Protein

Hintergrund:

Background: Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.

Synonym: Collagen triple helix repeat-containing protein 1,Protein NMTC1,CTHRC1

Molekulargewicht: 24.1 kDa

UniProt: Q96CG8

Pathways: Tube Formation