Coq7 Protein (His tag)

Produktnummer ABIN7319290

Produktdetails

Target: Coq7 (Coenzyme Q Biosynthesis Protein 7 (Coq7))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Coq7 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human COQ7 Protein (His Tag)

Sequenz: Ser37-Leu217

Produktmerkmale: Recombinant Human 5-demethoxyubiquinone hydroxylase, mitochondrial is produced by our Mammalian expression system and the target gene encoding Ser37-Leu217 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Coq7 (Coenzyme Q Biosynthesis Protein 7 (Coq7))

Andere Bezeichnung: COQ7 (Coq7 Produkte)

Synonyme: CAT5 Protein, CLK-1 Protein, CLK1 Protein, clk-1 Protein, coenzyme Q7, hydroxylase Protein, demethyl-Q 7 Protein, 5-demethoxyubiquinone hydroxylase, mitochondrial Protein, COQ7 Protein, Coq7 Protein, clk-1 Protein

Hintergrund:

Background: Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. COQ7 is involved in lifespan determination in ubiquinone-independent manner and also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. Human COQ7 protein contains 179 amino acids, is mostly helical, and contains an alpha-helical membrane insertion. It has been shown that mutations in the gene are associated with increased life span. Defects of the gene slow down a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging.

Synonym: Ubiquinone Biosynthesis Protein COQ7 Homolog, Coenzyme Q Biosynthesis Protein 7 Homolog, Timing Protein Clk-1 Homolog, COQ7,CAT5,CLK-1,CLK1

Molekulargewicht: 21.3 kDa

UniProt: Q99807

Pathways: Tube Formation