Coq7 Protein (AA 37-217) (His tag)

Produktnummer ABIN1096428

Produktdetails

Target: Coq7 (Coenzyme Q Biosynthesis Protein 7 (Coq7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 37-217

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Coq7 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human 5-Demethoxyubiquinone Hydroxylase, Mitochondrial/COQ7 (C-6His)

Sequenz: SGMTLDNISR AAVDRIIRVD HAGEYGANRI YAGQMAVLGR TSVGPVIQKM WDQEKDHLKK FNELMVTFRV RPTVLMPLWN VLGFALGAGT ALLGKEGAMA CTVAVEESIA HHYNNQIRTL MEEDPEKYEE LLQLIKKFRD EELEHHDIGL DHDAELAPAY AVLKSIIQAG CRVAIYLSER LVDHHHHHH

Produktmerkmale: Recombinant Human Ubiquinone Biosynthesis Protein COQ7 Homolog/COQ7 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser37-Leu217) of Human COQ7 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Coq7 (Coenzyme Q Biosynthesis Protein 7 (Coq7))

Andere Bezeichnung: coq7 (Coq7 Produkte)

Synonyme: CAT5 Protein, CLK-1 Protein, CLK1 Protein, clk-1 Protein, coenzyme Q7, hydroxylase Protein, demethyl-Q 7 Protein, 5-demethoxyubiquinone hydroxylase, mitochondrial Protein, COQ7 Protein, Coq7 Protein, clk-1 Protein

Sub Type: Fusionprotein

Hintergrund: Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. COQ7 is involved in lifespan determination in ubiquinone-independent manner and also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. Human COQ7 protein contains 179 amino acids, is mostly helical, and contains an alpha-helical membrane insertion. It has been shown that mutations in the gene are associated with increased life span. Defects of the gene slow down a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging.
Alternative Names: Ubiquinone Biosynthesis Protein COQ7 Homolog, Coenzyme Q Biosynthesis Protein 7 Homolog, Timing Protein Clk-1 Homolog, COQ7

Molekulargewicht: 21.3 kDa

UniProt: Q99807

Pathways: Tube Formation