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Cathepsin D Protein (CTSD) (His tag)

CTSD Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318253
  • Target Alle Cathepsin D (CTSD) Proteine anzeigen
    Cathepsin D (CTSD)
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Cathepsin D Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Cathepsin D/CTSD Protein (His Tag)
    Sequenz
    Leu21-Leu412
    Produktmerkmale
    Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSD Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Cathepsin D (CTSD)
    Andere Bezeichnung
    Cathepsin D/CTSD (CTSD Produkte)
    Synonyme
    catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
    Hintergrund

    Background: The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8 % ) compared with non-demented controls (4.9 %). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family

    Synonym: Cathepsin D, CTSD,CLN10,CPSD,HEL-S-130P

    Molekulargewicht
    43.8 kDa
    UniProt
    P07339
    Pathways
    Peptide Hormone Metabolism
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