B3GAT3 Protein (His tag)
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- Target Alle B3GAT3 Proteine anzeigen
- B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses B3GAT3 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human B3GAT3 Protein (His Tag)
- Sequenz
- Glu72-Val335
- Produktmerkmale
- Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 is produced by our E.coli expression system and the target gene encoding Glu72-Val335 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product B3GAT3 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaC,2 mM EDTA,20 % Glycerol, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))
- Andere Bezeichnung
- B3GAT3 (B3GAT3 Produkte)
- Synonyme
- GLCATI Protein, 2810405M13Rik Protein, GlcUAT-I Protein, Glcat-i Protein, beta-1,3-glucuronyltransferase 3 Protein, beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) Protein, B3GAT3 Protein, B3gat3 Protein
- Hintergrund
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Background: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3) is an enzyme that in humans is encoded by the B3GAT3 gene, belongs to the glycosyltransferase 43 family. B3GAT3 is involved in a number of biological processes such as catalyzing the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans, forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate, gGlycosaminoglycans biosynthesis, transfering a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans.It also plays a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins , hows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc and stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.
Synonym: B3GAT3,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3,Beta-1,3-glucuronyltransferase 3,Glucuronosyltransferase I,GlcAT-I,GlcUAT-I,Gal beta-1,3-Gal-R glucuronyltransferase,
- Molekulargewicht
- 30.4 kDa
- UniProt
- O94766
- Pathways
- Glycosaminoglycan Metabolic Process
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