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ATG4A Protein (His tag)

ATG4A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318185
  • Target Alle ATG4A Proteine anzeigen
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 2
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses ATG4A Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human ATG4A Protein (His Tag)
    Sequenz
    Met 1-Val398
    Produktmerkmale
    Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.
    Reinheit
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ATG4A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    Andere Bezeichnung
    ATG4A (ATG4A Produkte)
    Synonyme
    apg4a Protein, autl2 Protein, F6E13.27 Protein, APG4A Protein, zgc:111958 Protein, Aut2a Protein, AUTL2 Protein, AI627006 Protein, AV169859 Protein, Apg4a Protein, Atg4al Protein, Autl2 Protein, Atg4a Protein, autophagy related 4A cysteine peptidase L homeolog Protein, autophagy related 4A cysteine peptidase Protein, Peptidase family C54 protein Protein, ATG4 autophagy related 4 homolog A (S. cerevisiae) Protein, autophagy related 4A, cysteine peptidase Protein, atg4a.L Protein, ATG4A Protein, AT2G44140 Protein, atg4a Protein, Atg4a Protein
    Hintergrund

    Background: Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy, it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

    Synonym: Cysteine Protease ATG4A, AUT-Like 2 Cysteine Endopeptidase, Autophagin-2, Autophagy-Related Cysteine Endopeptidase 2, Autophagy-Related Protein 4 Homolog A, hAPG4A, ATG4A, APG4A, AUTL2

    Molekulargewicht
    47.5 kDa
    UniProt
    Q8WYN0
    Pathways
    Autophagie
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