Liver Arginase Protein (His tag)

Produktnummer ABIN7319955

Produktdetails

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Liver Arginase Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Arginase-1 Protein (His Tag)

Sequenz: 1M-322K

Produktmerkmale: A DNA sequence encoding the human Arginase-1 (1M-322K) was expressed with a polyhistidine tag at the N-terminus.

Reinheit: >90 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Liquid with sterile 25 mM Tris-HCl+150 mM KCl+1 mM DTT+20 % glycerol

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Samples are stable for up to twelve months from date of receipt at -70°C.Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: Arginase-1 (ARG1 Produkte)

Synonyme: SI:zC146F4.4 (novel protein with NUDIX domain) Protein, si:ch211-146f4.3 Protein, argi1 Protein, AI Protein, AI256583 Protein, Arg-1 Protein, PGIF Protein, arginase 1 Protein, arginase Protein, Arginase-1 Protein, arginase, liver Protein, L-arginase Protein, arg1 Protein, PGTG_16455 Protein, argi1 Protein, ARG1 Protein, Arg1 Protein

Hintergrund:

Background: Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver. Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.

Synonym: ARG1,Al,Arginase 1,Arginase liver,

Molekulargewicht: 36.9kDa

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin