MARCO Protein (His tag)
-
- Target Alle MARCO Proteine anzeigen
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Protein-Typ
- Recombinant
-
Spezies
- Cynomolgus
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses MARCO Protein ist gelabelt mit His tag.
- Verwendungszweck
- Cynomolgus MARCO Protein, His Tag
- Sequenz
- Met 79 - Ile 520
- Produktmerkmale
- Cynomolgus MARCO, His Tag (MAR-C5248) is expressed from human 293 cells (HEK293). It contains AA Met 79 - Ile 520 (Accession # A0A2K5X0Z2-1).
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MARCO Protein
-
Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)
MARCO Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 405-520) protein (His tag)MARCO Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 65-520) protein (His tag)Crystallography grade MARCO Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)Crystallography grade MARCO Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-520) protein (Strep Tag)Crystallography grade MARCO Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-518) protein (Strep Tag)Crystallography grade MARCO Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
-
- Applikationshinweise
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 45.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition due to glycosylation.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
-
- Target
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Andere Bezeichnung
- MARCO (MARCO Produkte)
- Synonyme
- AI323439 Protein, Ly112 Protein, Scara2 Protein, SCARA2 Protein, macrophage receptor with collagenous structure Protein, MARCO Protein, Marco Protein
- Hintergrund
-
Synonyms: MARCO, SCARA2, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2,
Description: MARCO is also known as Scavenger receptor class A member 2 and SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. MARCO ligation promotes the production of inflammatory mediators by macrophages. MARCO mediated internalization of some ligands prevents their activation of cell surface TLR4 but enables their activation of intracellular TLR3. MARCO contributes to the clearance of apoptotic cells and inhaled bacteria, mast cell mediated silicosis, and the amelioration of allergen or ozone induced lung inflammation. It is required for the organization of the splenic marginal zone and the interaction of splenic macrophages and B cells. - Molekulargewicht
- 45.6 kDa
- NCBI Accession
- XP_005573011
- Pathways
- Activation of Innate immune Response
-
