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CD8 alpha Protein (AA 22-182) (His tag)

CD8A Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN7013444
  • Target Alle CD8 alpha (CD8A) Proteine anzeigen
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 22-182
    Spezies
    • 15
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 14
    • 7
    • 5
    • 5
    • 3
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD8 alpha Protein ist gelabelt mit His tag.
    Produktmerkmale
    Human CD8 alpha / CD8A Protein, His Tag
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD8A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Andere Bezeichnung
    CD8 alpha (CD8A Produkte)
    Synonyme
    cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
    Hintergrund
    Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
    Molekulargewicht
    19.5 kDa
    NCBI Accession
    NP_001759
    Pathways
    T-Zell Rezeptor Signalweg
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