CCR8 Protein (Fc Tag)

Produktnummer ABIN6964400

Produktdetails

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CCR8 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human CCR8 with C-terminal human Fc tag

Spezifität: CCR8 (Met1-Lys35) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Haltbarkeit: 12 months

Antigendetails

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8 (CCR8 Produkte)

Synonyme: CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein

Hintergrund: Synonymes: CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 30.1 kDa after removal of the signal peptide.The apparent molecular mass of CCR8-hFc is 35-55 kDa due to glycosylation.

UniProt: P51685