CCR8 Protein (AA 1-35) (mFc Tag)

Produktnummer ABIN7274054

Produktdetails

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-35

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CCR8 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Human CCR8 Protein

Sequenz: Met1-Lys35

Produktmerkmale: Recombinant Human CCR8 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Met1-Lys35.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CCR8, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8 (CCR8 Produkte)

Synonyme: CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein

Hintergrund: CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.

Molekulargewicht: 30.25 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.