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ICOS Protein (AA 21-144) (Fc Tag)

ICOS Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN6938860
  • Target Alle ICOS Proteine anzeigen
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 21-144
    Spezies
    • 18
    • 10
    • 4
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ICOS Protein ist gelabelt mit Fc Tag.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ICOS Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Lagerung
    -20 °C
  • Target
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    Andere Bezeichnung
    ICOS (ICOS Produkte)
    Synonyme
    ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
    Hintergrund
    Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
    Molekulargewicht
    40.6 kDa
    Pathways
    Cancer Immune Checkpoints
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