ICOS Protein (AA 21-144) (Fc Tag)
-
- Target Alle ICOS Proteine anzeigen
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 21-144
-
Spezies
- Maus
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ICOS Protein ist gelabelt mit Fc Tag.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ICOS Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Lagerung
- -20 °C
-
- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Andere Bezeichnung
- ICOS (ICOS Produkte)
- Synonyme
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Hintergrund
- Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Molekulargewicht
- 40.6 kDa
- Pathways
- Cancer Immune Checkpoints
-