MERTK Protein (AA 21-505) (His tag)
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- Target Alle MERTK Proteine anzeigen
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 21-505
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses MERTK Protein ist gelabelt mit His tag.
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MERTK Protein
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C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 19-497) protein (His tag)
MERTK Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (mFc Tag)MERTK Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (His tag)MERTK Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 528-999) (Active) protein (GST tag)MERTK Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-120) protein (GST tag)MERTK Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) protein (Fc Tag)MERTK Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (Active) protein (GST tag,His tag)MERTK Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 96 % as determined by SDS-PAGE Active
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) protein (GST tag,His tag)MERTK Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE.
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (His tag)Crystallography grade MERTK Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 527-999) protein (His tag)Crystallography grade MERTK Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Andere Bezeichnung
- MERTK (MERTK Produkte)
- Synonyme
- MER Protein, RP38 Protein, c-mer Protein, Eyk Protein, Mer Protein, Nyk Protein, nmf12 Protein, rdy Protein, C-EYK Protein, MERTK Protein, DKFZp469D2215 Protein, si:ch1073-268l12.2 Protein, MER proto-oncogene, tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase a Protein, MERTK Protein, Mertk Protein, mertka Protein
- Hintergrund
- Tyrosine-protein kinase Mer(MERTK) is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
- Molekulargewicht
- 54.5 kDa
- NCBI Accession
- NP_006334
- Pathways
- RTK Signalweg
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