Hexokinase 1 Protein (HK1) (His tag)

Produktnummer ABIN668037

Produktdetails

Target: Hexokinase 1 (HK1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Hexokinase 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Hexokinase 1 Human, His-tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl pH8.0, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: Hexokinase 1 (HK1)

Andere Bezeichnung: Hexokinase 1 (HK1 Produkte)

Synonyme: HK1-ta Protein, HK1-tb Protein, HK1-tc Protein, HKD Protein, HKI Protein, HMSNR Protein, HXK1 Protein, Hexokinase Protein, hk1 Protein, HEX Protein, HEX-1 Protein, HK Protein, ARABIDOPSIS THALIANA HEXOKINASE 1 Protein, ATHXK1 Protein, F19B15.160 Protein, F19B15_160 Protein, GIN2 Protein, GLUCOSE INSENSITIVE 2 Protein, HEXOKINASE Protein, hexokinase 1 Protein, im:7148527 Protein, wu:fc09d08 Protein, wu:fc16e02 Protein, wu:fc21e02 Protein, wu:fq14b11 Protein, zgc:55790 Protein, zgc:77618 Protein, hexokinase-1 Protein, HK1 Protein, BB404130 Protein, Hk-1 Protein, Hk1-s Protein, dea Protein, mHk1-s Protein, HEXOKIN Protein, Hxk1 Protein, NtHxK1 Protein, NtHxk Protein, hexokinase Protein, StHK1 Protein, hxk Protein, hk1-A Protein, hexokinase 1 Protein, hexokinase-1 Protein, Hexokinase 1 Protein, hexokinase 1, putative Protein, hexokinase 1 L homeolog Protein, HK1 Protein, hk1 Protein, LOC100136279 Protein, Hex1 Protein, HXK1 Protein, Hk1 Protein, TA19800 Protein, hxk1 Protein, LOC107797523 Protein, LOC102604144 Protein, hk1.L Protein

Hintergrund: Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase1 is found in the adipose tissue and liver and encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this hexokinase1 have been associated with hemolytic anemia due to hexokinase deficiency. Recombinant human Hexokinase1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HK1, Hexokinase 1, EC 2.7.1.1, Hexokinase type I, HK I, Brain form hexokinase, Hexokinase-1, BB404130, dea, Glycolytic enzyme, HEXOKIN, Hexokinase PI, Hexokinase type I, Hexokinase, tumor isozyme, Hexokinase-A, HK1 tb, Hk1-s, HK1-ta, HK1-tc, HKI, HXK1, mHk1-s. NCBI no.: NP_000179

Molekulargewicht: 104.6kDa (937aa)

Pathways: Carbohydrate Homeostasis, Warburg Effekt