AFT1 Protein (AA 1-271) (His tag)

Produktnummer ABIN668009

Produktdetails

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-271

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses AFT1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ATF1, 1-271aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA

Lagerung: 4 °C

Antigendetails

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Andere Bezeichnung: ATF1 (AFT1 Produkte)

Synonyme: ews-atf1 Protein, fus/atf-1 Protein, treb36 Protein, ATF1 Protein, EWS-ATF1 Protein, FUS/ATF-1 Protein, TREB36 Protein, Atf-1 Protein, wu:fc92c07 Protein, zgc:64099 Protein, activating transcription factor 1 Protein, activating transcription factor 1 L homeolog Protein, atf1 Protein, ATF1 Protein, MGC85066 Protein, atf1.L Protein, Atf1 Protein

Hintergrund: Activating transcription factor 1, also known as ATF1, is a cyclic-AMP dependent transcription factor. ATF1 is expressed in a wide variety of cell types and is capable of dimerizing with CREB. MSK1 and MSK2 protein kinases are required for the stress-induced phosphorylation of transcription factors CREB and ATF1 in primary embryonic fibroblasts. Epidermal growth factor induction of c-jun expression requires ATF1 and MEF2 sites in the c-jun promoter. Recombinant human ATF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Activating transcription factor 1, EWS-ATF1, FUS/ATF-1, TREB36. NCBI no.: NP_005162

Molekulargewicht: 31.8 kDa (295aa) confirmed by MALDI-TOF

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades