POLL Protein (AA 1-300) (His tag)

Produktnummer ABIN7279597

Produktdetails

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-300

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses POLL Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: POLL, 1-300aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Andere Bezeichnung: POLL (POLL Produkte)

Synonyme: T10O24.13 Protein, T10O24_13 Protein, zgc:66320 Protein, zgc:77901 Protein, wu:fe49a04 Protein, beta-n Protein, pol-kappa Protein, BETAN Protein, POLKAPPA Protein, 1110003P06Rik Protein, AV007317 Protein, DNA polymerase lambda (POLL) Protein, DNA polymerase lambda Protein, polymerase (DNA directed), lambda Protein, polymerase (DNA) lambda Protein, Pol{lambda} Protein, PTRG_00468 Protein, poll Protein, POLL Protein, MCYG_03796 Protein, LOC9325878 Protein, MGYG_02138 Protein, Poll Protein

Hintergrund: DNA polymerase lambda, also known as POLL, is a DNA polymerase involved in base excision repair (BER). POLL is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. In addition, POLL may play a role in the mutagenic bypass of T-T dimers. Pol lambda possesses terminal transferase and 5’-deoxyribose-5-phosphate lyase activity. These activities have been found to be coordinated by PCNA and replication protein A. Recombinant human POLL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA polymerase lambda, BETA-N, POL-KAPPA. NCBI no.: AAH03548

Molekulargewicht: 36 kDa (320aa), confirmed by MALDI-TOF

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response