QDPR Protein (AA 1-244) (His tag)

Produktnummer ABIN667949

Produktdetails

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-244

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses QDPR Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: QDPR, 1-244aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT.

Lagerung: 4 °C

Antigendetails

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Andere Bezeichnung: QDPR (QDPR Produkte)

Synonyme: DHPR Protein, PKU2 Protein, SDR33C1 Protein, 2610008L04Rik Protein, D5Ertd371e Protein, Dhpr Protein, QDPR Protein, qdpr Protein, MGC131372 Protein, DDBDRAFT_0168923 Protein, DDBDRAFT_0237752 Protein, DDB_0168923 Protein, DDB_0237752 Protein, CG4665 Protein, Dmel\\CG4665 Protein, si:ch211-89f22.2 Protein, quinoid dihydropteridine reductase Protein, quinoid dihydropteridine reductase S homeolog Protein, dihydropteridine reductase Protein, Dihydropteridine reductase Protein, bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB Protein, quinoid dihydropteridine reductase a Protein, QDPR Protein, Qdpr Protein, qdpr Protein, qdpr.S Protein, Dhpr Protein, nfnB Protein, LOC5568428 Protein, dhpr Protein, qdpra Protein

Hintergrund: QDPR is a member of the short-chain dehydrogenases/reductase(SDR) family of enzymes. Functioning as a homodimer, QDPR plays an important role in the recycling of tetrahydrobiopterin (BH4), an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine). More specifically, QDPR catalyzes the regeneration of BH4 from quinonoid dihydrobiopterin (qBH2), the product generated from the hydroxylation reactions. Mutations in the gene encoding QDPR can lead to phenylketonuria II. Recombinant human QDPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Quinoid dihydropteridine reductase., DHPR, FLJ42391, PKU2, SDR33C1. NCBI no.: NP_000311

Molekulargewicht: 28.2 kDa (267aa), confirmed by MALDI-TOF