QDPR Protein (AA 1-244) (His tag)

Produktnummer ABIN4370714

Produktdetails

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-244

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses QDPR Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Dihydropteridine Reductase/QDPR (C-6His)

Sequenz: AAAAAAGEAR RVLVYGGRGA LGSRCVQAFR ARNWWVASVD VVENEEASAS IIVKMTDSFT EQADQVTAEV GKLLGEEKVD AILCVAGGWA GGNAKSKSLF KNCDLMWKQS IWTSTISSHL ATKHLKEGGL LTLAGAKAAL DGTPGMIGYG MAKGAVHQLC QSLAGKNSGM PPGAAAIAVL PVTLDTPMNR KSMPEADFSS WTPLEFLVET FHDWITGKNR PSSGSLIQVV TTEGRTELTP AYFVDHHHHH H

Produktmerkmale: Recombinant Human Dihydropteridine Reductase/QDPR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Phe244) of Human QDPR fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Andere Bezeichnung: QDPR (QDPR Produkte)

Synonyme: DHPR Protein, PKU2 Protein, SDR33C1 Protein, 2610008L04Rik Protein, D5Ertd371e Protein, Dhpr Protein, QDPR Protein, qdpr Protein, MGC131372 Protein, DDBDRAFT_0168923 Protein, DDBDRAFT_0237752 Protein, DDB_0168923 Protein, DDB_0237752 Protein, CG4665 Protein, Dmel\\CG4665 Protein, si:ch211-89f22.2 Protein, quinoid dihydropteridine reductase Protein, quinoid dihydropteridine reductase S homeolog Protein, dihydropteridine reductase Protein, Dihydropteridine reductase Protein, bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB Protein, quinoid dihydropteridine reductase a Protein, QDPR Protein, Qdpr Protein, qdpr Protein, qdpr.S Protein, Dhpr Protein, nfnB Protein, LOC5568428 Protein, dhpr Protein, qdpra Protein

Sub Type: Fusionprotein

Hintergrund: Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals in the brain called neurotransmitters, which transmit signals between nerve cells. Defects in QDPR are the cause of BH4-deficient hyperphenylalaninemia type C (HPABH4C) which is a rare autosomal recessive disorder and is lethal.
Alternative Names: Dihydropteridine Reductase, HDHPR, Quinoid Dihydropteridine Reductase, QDPR, DHPR

Molekulargewicht: 26.8 kDa

UniProt: P09417