HMGA1 Protein (AA 1-107) (His tag)

Produktnummer ABIN667938

Produktdetails

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-107

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HMGA1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: HMGA1, 1-107aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.2M NaCl

Lagerung: 4 °C

Antigendetails

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Andere Bezeichnung: HMGA1 (HMGA1 Produkte)

Synonyme: HMG-R Protein, HMGA1A Protein, HMGIY Protein, Hmgi Protein, Hmgiy Protein, hmga1 Protein, hmgiy Protein, wu:fb12b06 Protein, wu:fb18f11 Protein, wu:fc19f01 Protein, wu:fi38b05 Protein, zgc:85677 Protein, AL023995 Protein, Hmga1a Protein, Hmga1b Protein, Hmgy Protein, HMG-I(Y) Protein, HMG-Y Protein, HMGA1 Protein, zgc:153948 Protein, high mobility group AT-hook 1 Protein, high mobility group protein HMG-I/HMG-Y Protein, high mobility group AT-hook 1a Protein, high mobility group AT-hook 1b Protein, HMGA1 Protein, Hmga1 Protein, TSC_c24220 Protein, hmga1a Protein, LOC705105 Protein, hmga1b Protein

Hintergrund: High mobility group protein HMG-I/HMG-Y, also known as HMGA1, is a member of the non-histone chromosomal high mobility group protein (HMG) family. HMGA1 consists of a highly conserved AT-hook DNA-binding domain that mediates binding to AT-rich sequences in the minor groove of chromosomal DNA. It functions as architectural chromatin-binding transcription factor altering the conformation of DNA by modulating nuclear protein-DNA complexes. It is involved in many cellular processes including growth regulation, viral induction of beta-IFN gene and regulation of inducible gene transcription. Recombinant human HMGA1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: High mobility group protein HMG-I/HMG-Y, HMG-R, HMGA1A, HMGIY. NCBI no.: NP_665906

Molekulargewicht: 12.7 kDa (115aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: Nuclear Hormone Receptor Binding, Autophagie