HSD17B11 Protein (AA 20-285) (His tag)

Produktnummer ABIN667857

Produktdetails

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-285

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HSD17B11 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: HSD17B11, 20-285aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Andere Bezeichnung: HSD17B11 (HSD17B11 Produkte)

Synonyme: 17BHSD11 Protein, DHRS8 Protein, PAN1B Protein, RETSDR2 Protein, SDR16C2 Protein, Dhrs8 Protein, HSD17B13 Protein, MGC84756 Protein, HSD17B11 Protein, Pan1b Protein, SDR2 Protein, retSDR2 Protein, 17-beta-HSD 11 Protein, 17-beta-HSD XI Protein, 17bHSD11 Protein, 17betaHSD11 Protein, 17betaHSDXI Protein, hydroxysteroid 17-beta dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog Protein, estradiol 17-beta-dehydrogenase 11 Protein, HSD17B11 Protein, Hsd17b11 Protein, hsd17b11.L Protein, hsd17b11 Protein, LOC100348005 Protein, LOC100520923 Protein

Hintergrund: HSD17B11, also known as DHRS8 (dehydrogenase/reductase SDR family member 8), belongs to the HSD17B family of proteins, which regulate the availability of steroids within various tissues throughout the body. It is widely expressed with highest levels found in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart as well as in steroidogenic cells. This protein converts androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone, suggesting it may participate in androgen metabolism during steroidogenesis. Recombinant human HSD17B11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Hydroxysteroid (17-beta) dehydrogenase 11, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2. NCBI no.: NP_057329

Molekulargewicht: 31.4 kDa (287aa), confirmed by MALDI-TOF