HSD17B11 Protein (AA 20-300) (His-SUMO Tag)

Produktnummer ABIN5711619

Produktdetails

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-300

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HSD17B11 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ESFVKLFIPK RRKSVTGEIV LITGAGHGIG RLTAYEFAKL KSKLVLWDIN KHGLEETAAK CKGLGAKVHT FVVDCSNRED IYSSAKKVKA EIGDVSILVN NAGVVYTSDL FATQDPQIEK TFEVNVLAHF WTTKAFLPAM TKNNHGHIVT VASAAGHVSV PFLLAYCSSK FAAVGFHKTL TDELAALQIT GVKTTCLCPN FVNTGFIKNP STSLGPTLEP EEVVNRLMHG ILTEQKMIFI PSSIAFLTTL ERILPERFLA VLKRKISVKF DAVIGYKMKA Q

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Andere Bezeichnung: DHB11 (HSD17B11 Produkte)

Synonyme: 17BHSD11 Protein, DHRS8 Protein, PAN1B Protein, RETSDR2 Protein, SDR16C2 Protein, Dhrs8 Protein, HSD17B13 Protein, MGC84756 Protein, HSD17B11 Protein, Pan1b Protein, SDR2 Protein, retSDR2 Protein, 17-beta-HSD 11 Protein, 17-beta-HSD XI Protein, 17bHSD11 Protein, 17betaHSD11 Protein, 17betaHSDXI Protein, hydroxysteroid 17-beta dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog Protein, estradiol 17-beta-dehydrogenase 11 Protein, HSD17B11 Protein, Hsd17b11 Protein, hsd17b11.L Protein, hsd17b11 Protein, LOC100348005 Protein, LOC100520923 Protein

Hintergrund: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Molekulargewicht: 46.8 kDa

UniProt: Q8NBQ5