LAMTOR2 Protein (AA 1-125) (His tag)

Produktnummer ABIN667853

Produktdetails

Target: LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-125

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LAMTOR2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ROBLD3, 1-125aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 2mM DTT, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))

Andere Bezeichnung: ROBLD3 (LAMTOR2 Produkte)

Synonyme: ENDAP Protein, HSPC003 Protein, MAPBPIP Protein, MAPKSP1AP Protein, ROBLD3 Protein, Ragulator2 Protein, p14 Protein, 2010111E04Rik Protein, AL022628 Protein, Mapbpip Protein, P14 Protein, Rab25 Protein, Robld3 Protein, RGD1562501 Protein, cg5189 Protein, endap Protein, hspc003 Protein, mapbpip Protein, mapbpip-B Protein, mapksp1ap Protein, ragulator2 Protein, robld3 Protein, robld3-b Protein, zgc:100811 Protein, lamtor2 Protein, lamtor2-a Protein, lamtor2-b Protein, mapbpip-A Protein, robld3-a Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 S homeolog Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 L homeolog Protein, LAMTOR2 Protein, Lamtor2 Protein, lamtor2.S Protein, lamtor2 Protein, lamtor2.L Protein

Hintergrund: ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes. Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitogen-activated protein-binding protein-interacting protein, ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, p14. NCBI no.: NP_054736

Molekulargewicht: 16.0 kDa (149aa), confirmed by MALDI-TOF

Pathways: PI3K-Akt Signalweg