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BAG3 Protein (AA 1-575) (His tag)

BAG3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667755
  • Target Alle BAG3 Proteine anzeigen
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-575
    Spezies
    • 5
    • 3
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BAG3 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    BAG3, 1-575aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product BAG3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM EDTA, 0.1mM PMSF, 10% glycerol
    Lagerung
    4 °C
  • Target
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Andere Bezeichnung
    BAG3 (BAG3 Produkte)
    Synonyme
    bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein
    Hintergrund
    BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Also, it has been shown to diminish stress-induced apoptosis. Recombinant human BAG3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: BIS, CAIR-1, BAG family molecular chaperone regulator 3 BAG 3, Bcl 2 binding protein, BCL2 associated athanogene 3, BCL2 binding athanogene 3, Docking protein CAIR 1. NCBI no.: NP_004272
    Molekulargewicht
    63.7 kDa (595aa)
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