BAG3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715135

Produktdetails

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BAG3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human BAG3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Andere Bezeichnung: Bag3 (BAG3 Produkte)

Synonyme: bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein

Hintergrund: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Molekulargewicht: 61.4 kDa

NCBI Accession: NP_004272