ARPC5 Protein (AA 1-151) (His tag)

Produktnummer ABIN667461

Produktdetails

Target: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-151

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ARPC5 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ARPC5, 1-151aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Andere Bezeichnung: ARPC5 (ARPC5 Produkte)

Synonyme: arc16 Protein, p16-arc Protein, ARPC5 Protein, APOBEC4 Protein, ARC16 Protein, dJ127C7.3 Protein, p16-Arc Protein, MGC86407 Protein, 5830443F10Rik Protein, arpc5 Protein, fb09c07 Protein, fb12b05 Protein, fc56c07 Protein, wu:fb09c07 Protein, wu:fb12b05 Protein, wu:fc56c07 Protein, actin related protein 2/3 complex subunit 5 Protein, actin related protein 2/3 complex subunit 5 L homeolog Protein, actin related protein 2/3 complex, subunit 5 Protein, actin related protein 2/3 complex, subunit 5B Protein, actin related protein 2/3 complex, subunit 5A Protein, ARPC5 Protein, arpc5 Protein, arpc5.L Protein, Arpc5 Protein, arpc5b Protein, arpc5a Protein

Hintergrund: P16-ARC, also known as ARPC5, is a 151 amino acid subunit of the Arp2/3 complex. Thought to play a role in maintaining the integrity of Arp2/3, ARPC5 is a substrate for MAPKAPK-2 which, through phosphorylation of ARPC5, may participate in Arp2/3 regulatory functions and remodeling of the Actin cytoskeleton. Two isoforms of ARPC5 exist due to alternative splicing events. Recombinant human ARPC5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Actin related protein 2/3 complex, subunit 5, p16-ARC, ARC16. NCBI no.: NP_005708

Molekulargewicht: 18.4 kDa (171aa), confirmed by MALDI-TOF

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization