CIRBP Protein (AA 1-172) (His tag)

Produktnummer ABIN667435

Produktdetails

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-172

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CIRBP Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: CIRBP, 1-172aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay )

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Andere Bezeichnung: CIRBP (CIRBP Produkte)

Synonyme: CIRP Protein, Cirp Protein, R74941 Protein, Xcirp Protein, cirbp Protein, cirbp-a Protein, cirbp2 Protein, cirp Protein, cirp1 Protein, cirp2 Protein, xcirp2 Protein, XCIRP Protein, XCIRP-1 Protein, cirbp-b Protein, cirp-1 Protein, APBP-1 Protein, zgc:136559 Protein, CIRBP Protein, A18 hnRNP Protein, cold inducible RNA binding protein Protein, cold-inducible RNA-binding protein Protein, cold inducible RNA binding protein S homeolog Protein, cold inducible RNA binding protein L homeolog Protein, cold inducible RNA binding protein b Protein, CIRBP Protein, EDI_107320 Protein, Cirbp Protein, cirbp.S Protein, cirbp.L Protein, cirbp Protein, cirbpb Protein

Hintergrund: Cold inducible RNA-binding protein, also known as CIRBP, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It is localizes to the nucleus and contains one RRM (RNA recognition motif) domain. Expressed ubiquitously, CIRBP is thought to play an essential role in the suppression of cellular proliferation in response to UV irradiation or extreme cold. Recombinant human CIRBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cold inducible RNA-binding protein, CIRP, A18HNRNP. NCBI no.: NP_001271

Molekulargewicht: 20.8 kDa (192aa) confirmed by MALDI-TOF

Pathways: Ribonucleoprotein Complex Subunit Organization