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SH2D1A Protein (AA 1-128) (His tag)

SH2D1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667264
  • Target Alle SH2D1A Proteine anzeigen
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-128
    Spezies
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses SH2D1A Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    SH2D1A, 1-128aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product SH2D1A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 10% Glycerol
    Lagerung
    4 °C
  • Target
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Andere Bezeichnung
    SH2D1A (SH2D1A Produkte)
    Synonyme
    DSHP Protein, EBVS Protein, IMD5 Protein, LYP Protein, MTCP1 Protein, SAP Protein, SAP/SH2D1A Protein, XLP Protein, XLPD Protein, RGD1562408 Protein, Gm686 Protein, SH2D1A Protein, SH2 domain containing 1A Protein, SH2D1A Protein, Sh2d1a Protein
    Hintergrund
    SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD. NCBI no.: NP_002342
    Molekulargewicht
    16.3 kDa(148aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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