PSME1 Protein (AA 1-249) (His tag)

Produktnummer ABIN667239

Produktdetails

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-249

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PSME1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PSME1, 1-249aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Andere Bezeichnung: PSME1 (PSME1 Produkte)

Synonyme: fk89d05 Protein, wu:fk89d05 Protein, IFI5111 Protein, PA28A Protein, PA28alpha Protein, REGalpha Protein, AW413925 Protein, PA28a Protein, proteasome activator subunit 1 Protein, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Protein, psme1 Protein, PSME1 Protein, Psme1 Protein

Hintergrund: PSME1 is an interferon gamma (IFNG) inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an alternative proteasome activator that does not employ the use of ubiquitin. The PSME1 complex is composed of two homologous subunits, alpha and beta, which have similar catalytic properties and associate to form a hexameric ring. Recombinant human PSME1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Proteasome activator complex subunit 1, IFI5111, MGC8628, PA28A, PA28alpha, REGalpha. NCBI no.: NP_006254

Molekulargewicht: 30.8kDa (269aa) confirmed by MALDI-TOF

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA