PSME1 Produkte
(Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
Kategorien
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Ausgewählte PSME1 Kategorien
PSME1 Antikörper
High quality antibodies with extensive validation data.
PSME1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PSME1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, IP
Validierungen
- (4)
Kat. Nr.
ABIN7164913
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN651448
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN519415
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene PSME1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975639
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951630
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PSME1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124618
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316661
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3121168
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PSME1 Produkten
: "Modular expression analysis reveals functional conservation between human Langerhans cells and mouse cross-priming dendritic cells." in: The Journal of experimental medicine, Vol. 212, Issue 5, pp. 743-57, (2015) (PubMed).: "Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma." in: Blood, Vol. 117, Issue 24, pp. 6638-49, (2011) (PubMed).
: "Anti-20S proteasome autoantibodies inhibit proteasome stimulation by proteasome activator PA28." in: Arthritis and rheumatism, Vol. 54, Issue 7, pp. 2175-83, (2006) (PubMed).
Synonyme und alternative Namen zu PSME1
proteasome activator subunit 1 (psme1), proteasome activator subunit 1 (PSME1), proteasome activator subunit 1 (Psme1), proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (Psme1), AW413925, fk89d05, IFI5111, PA28A, PA28a, PA28alpha, REGalpha, wu:fk89d05Bezeichner auf Proteinebene für PSME1
- proteasome activator complex subunit 1
- pA23-a
- proteasome activator subunit 1
- 11S regulator complex subunit alpha
- PA28a
- PA28alpha
- REG-alpha
- activator of multicatalytic protease subunit 1
- protease (prosome, macropain) 28 subunit, alpha
- proteasome (prosome, macropain) 28 subunit, alpha
- proteasome activator 28 subunit alpha
- 29-kD MCP activator subunit
- IGUP I-5111
- interferon gamma up-regulated I-5111 protein
- interferon-gamma IEF SSP 5111
- interferon-gamma-inducible protein 5111
- PA28 alpha subunit
- proteasome activator 28 alpha subunit
- proteasome activator PA28 alpha subunit
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