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PSME3 Produkte

(PSME3)

Kategorien

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].

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Ausgewählte PSME3 Kategorien

PSME3 Antikörper

High quality antibodies with extensive validation data.

PSME3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PSME3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PSME3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7441328
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (6)
Kat. Nr. ABIN2856424
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN7164919
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PSME3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958989
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1150397
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Pig
Analytical Method
Validierungen
Kat. Nr. ABIN1150398
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PSME3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124706
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124704
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7279625
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PSME3 Produkten

Li, Dang, Zhang, Yan, Zhai, Chen, Li, Tong, Gao, Amjad, Ji, Jing, Jiang, Shi, Yao, Song, Liu, Yang, Yang, Cai, Xu, Huang, He, Liu, Chen, Moses, Fu, Xiao, Li: "REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway." in: Nature communications, Vol. 6, pp. 6875, (2015) (PubMed).

Ko, Taylor, Bellon, Bai, Shevtsov, Dundr, Nicot: "PA28γ is a novel corepressor of HTLV-1 replication and controls viral latency." in: Blood, Vol. 121, Issue 5, pp. 791-800, (2013) (PubMed).

Matsudaira, Takeuchi, Takasaki, Yano, Matsushita, Hashimoto: "Relationships between autoantibody responses to deletion mutants of Ki antigen and clinical manifestations of lupus." in: The Journal of rheumatology, Vol. 30, Issue 6, pp. 1208-14, (2003) (PubMed).

Kohda, Ishibashi, Shimbara, Tanaka, Matsuda, Kasahara et al.: "Characterization of the mouse PA28 activator complex gene family: complete organizations of the three member genes and a physical map of the approximately 150-kb region containing the alpha- and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 10, pp. 4923-35, (1998) (PubMed).

Synonyme und alternative Namen zu PSME3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) (Psme3), proteasome activator subunit 3 (Psme3), proteasome activator subunit 3 (PSME3), proteasome activator subunit 3 S homeolog (psme3.S), AA410043, Ab2-371, AU020960, Ki, PA28-gamma, pa28g, PA28G, PA28gamma, psme3b, REG-GAMMA, REGgamma

Bezeichner auf Proteinebene für PSME3

  • 11S regulator complex subunit gamma
  • REG-gamma
  • activator of multicatalytic protease subunit 3
  • ki nuclear autoantigen
  • proteaseome (prosome, macropain) 28 subunit, 3
  • proteasome activator 28 subunit gamma
  • proteasome activator complex subunit 3
  • 11S regulator complex gamma subunit
  • Ki antigen
  • Ki nuclear autoantigen
  • PA28 gamma variant 5
  • proteasome activator 28-gamma
  • PA28g
  • PA28gamma
  • proteasome activator subunit 3
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