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CRADD Protein (AA 1-199) (His tag)

CRADD Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667087
  • Target Alle CRADD Proteine anzeigen
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-199
    Spezies
    • 7
    • 1
    Human
    Quelle
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CRADD Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    CRADD, 1-199aa, Human,His tagged, Recombinant, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CRADD Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid in 20mM TRIS pH 8.0, 20% glycerol
    Lagerung
    4 °C
  • Target
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Andere Bezeichnung
    CRADD (CRADD Produkte)
    Synonyme
    cradd Protein, MGC89035 Protein, zgc:101717 Protein, CRADD Protein, DKFZp468A2219 Protein, LOC100226369 Protein, raidd Protein, MGC78788 Protein, MRT34 Protein, RAIDD Protein, CASP2 and RIPK1 domain containing adaptor with death domain Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 1 Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog Protein, CRADD Protein, cradd.1 Protein, cradd Protein, cradd.2.S Protein, Cradd Protein
    Hintergrund
    CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recombinant CRADD protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: RAIDD, CRADD, Caspase and RIP adapter with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, Death adaptor molecule RAIDD, Death domain containing protein CRADD, MGC9163, RIP associated ICH1/CED3 homologous protein with death domain, RIP associated protein with a death domain,. NCBI no.: NP_003796
    Molekulargewicht
    24.9kDa (219aa), confirmed by MALDI-TOF.
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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