PTTG1 Protein (AA 1-202) (His tag)

Produktnummer ABIN666649

Produktdetails

Target: PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-202

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PTTG1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PTTG1, 1-202 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

Andere Bezeichnung: PTTG1 (PTTG1 Produkte)

Synonyme: EAP1 Protein, HPTTG Protein, PTTG Protein, TUTR1 Protein, PTTG1 Protein, securin Protein, AW555095 Protein, C87862 Protein, Pttg Protein, Pttg3 Protein, Securin Protein, Protein Cut2 Protein, pituitary tumor-transforming 1 Protein, pituitary tumor-transforming gene 1 Protein, securin, sister chromatid separation inhibitor Protein, PTTG1 Protein, Pttg1 Protein, cut2 Protein

Hintergrund: PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles, the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EAP1, HPTTG, PTTG, TUTR1, SECURIN, Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1, Esp1-associated protein, MGC126883, MGC138276, Pds1, PTTG1 protein, PTTG1, Pituitary tumor transforming 1, PTTG 1, EAP 1, Cut2, Pituitary tumor transforming protein 1, AW555095, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor-transforming 1, isoform CRA_b, hPTTG, Pituitary tumor-transforming gene 1, TUTR 1, Pttg3, Pituitary tumor-transforming gene 1 protein, C87862, TUMOR TRANSFORMING 1, Tumor transforming protein 1,. NCBI no.: NP_004210

Molekulargewicht: 24.1 kDa (222aa), confirmed by MALDI-TOF.