AES Protein (AA 1-197) (His tag)

Produktnummer ABIN666634

Produktdetails

Target: AES (Amino-terminal Enhancer of Split (AES))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-197

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses AES Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: AES, 1-197aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: AES (Amino-terminal Enhancer of Split (AES))

Andere Bezeichnung: AES (AES Produkte)

Synonyme: AES-1 Protein, AES-2 Protein, ESP1 Protein, GRG Protein, GRG5 Protein, TLE5 Protein, AL024115 Protein, Esp1 Protein, Grg Protein, Grg-5 Protein, Grg5 Protein, Tle5 Protein, zgc:64216 Protein, aes-1 Protein, aes-2 Protein, esp1 Protein, grg Protein, grg5 Protein, tle5 Protein, xgrg-5 Protein, AES Protein, amino-terminal enhancer of split Protein, amino-terminal enhancer of split S homeolog Protein, AES Protein, Aes Protein, aes Protein, aes.S Protein

Hintergrund: Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Recombinant human AES protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Amino-terminal enhancer of split, AES-1, AES-2, ESP1, GRG, GRG5, TLE5, Groucho homologue. NCBI no.: NP_001121

Molekulargewicht: 24.1 kDa (217aa) confirmed by MALDI-TOF

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom