CD161 Protein (AA 67-225) (hIgG-His-tag)

Produktnummer ABIN7529374

Produktdetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 67-225

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses CD161 Protein ist gelabelt mit hIgG-His-tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPQKSSIEK CSVDIQQSRN KTTERPGLLN CPIYWQQLRE KCLLFSHTVN PWNNSLADCS TKESSLLLIR DKDELIHTQN LIRDKAILFW IGLNFSLSEK NWKWINGSFL NSNDLEIRGD AKENSCISIS QTSVYSEYCS TEIRWICQKE LTPVRNKVYP DSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Andere Bezeichnung: KLRB1 (KLRB1 Produkte)

Synonyme: NKR-P1 Protein, KLRB1 Protein, 4930431A04Rik Protein, Gm4696 Protein, Klrb1g Protein, Klrb6 Protein, Ly-55 Protein, Ly55 Protein, NKR-P1G Protein, Nkrp-1e Protein, Nkrp1g Protein, CD161 Protein, CLEC5B Protein, NKR Protein, NKR-P1A Protein, NKRP1A Protein, hNKR-P1A Protein, Klrb1d Protein, Klrb1f Protein, Nkr-p1e Protein, killer cell lectin like receptor B1 Protein, killer cell lectin-like receptor subfamily B member 1 Protein, killer cell lectin-like receptor subfamily B, member 1 Protein, KLRB1 Protein, Klrb1 Protein

Hintergrund: KLRB1, also known as killer cell lectin-like receptor subfamily B member 1, is classified as a type II membrane protein because it has an external C terminus. It is expressed by NK cells and may be involved in the regulation of NK cell function. It plays a novel and important role in B cell maturation within the GC in humans. It is expressed by lymphocytes found in human gut and liver, as well as blood, especially natural killer (NK) cells, T helper 17 (Th17) cells, and a population of unconventional T cells known as mucosal-associated invariant T (MAIT) cells. It is also expressed, at intermediate levels, on a prominent subset of polyclonal CD8+ T cells, including antiviral populations that display a memory phenotype. Recombinant human KLRB1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 45.7kDa (401aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002249

UniProt: Q12918