CD161 Protein (AA 67-227) (His-Avi Tag,Biotin)

Produktnummer ABIN7274062

Produktdetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 67-227

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD161 Protein ist gelabelt mit His-Avi Tag,Biotin.

Verwendungszweck: Biotinylated Cynomolgus CD161 Protein

Sequenz: Gln67-Leu227

Produktmerkmale: Recombinant Biotinylated Cynomolgus CD161 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln67-Leu227.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Biotinylated Cynomolgus CD161, His Tag at 0.5μg/ml (100μl/Well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Andere Bezeichnung: CD161 (KLRB1 Produkte)

Synonyme: NKR-P1 Protein, KLRB1 Protein, 4930431A04Rik Protein, Gm4696 Protein, Klrb1g Protein, Klrb6 Protein, Ly-55 Protein, Ly55 Protein, NKR-P1G Protein, Nkrp-1e Protein, Nkrp1g Protein, CD161 Protein, CLEC5B Protein, NKR Protein, NKR-P1A Protein, NKRP1A Protein, hNKR-P1A Protein, Klrb1d Protein, Klrb1f Protein, Nkr-p1e Protein, killer cell lectin like receptor B1 Protein, killer cell lectin-like receptor subfamily B member 1 Protein, killer cell lectin-like receptor subfamily B, member 1 Protein, KLRB1 Protein, Klrb1 Protein

Hintergrund: CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment.

Molekulargewicht: 21.5 kDa. Due to glycosylation, the protein migrates to 37-42 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_005570142