Kallikrein 15 Protein (AA 17-256) (His tag)

Produktnummer ABIN6388017

Produktdetails

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Protein-Typ: Recombinant

Proteineigenschaft: AA 17-256

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses Kallikrein 15 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPQDGDKLL EGDECAPHSQ PWQVALYERG RFNCGASLIS PHWVLSAAHC QSRFMRVRLG EHNLRKRDGP EQLRTTSRVI PHPRYEARSH RNDIMLLRLV QPARLNPQVR PAVLPTRCPH PGEACVVSGW GLVSHNEPGT AGSPRSQVSL PDTLHCANIS IISDTSCDKS YPGRLTNTMV CAGAEGRGAE SCEGDSGGPL VCGGILQGIV SWGDVPCDNT TKPGVYTKVC HYLEWIRETM KRNHHHHHH

Reinheit: > 80 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Andere Bezeichnung: KLK15 (KLK15 Produkte)

Synonyme: ACO Protein, HSRNASPH Protein, kallikrein related-peptidase 15 Protein, kallikrein related peptidase 15 Protein, kallikrein-related peptidase 15 Protein, Klk15 Protein, KLK15 Protein

Hintergrund: KLK15, also known as kallikrein-15 isoform 4, is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. Also, growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, it has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. Recombinant human KLK15, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 27.4kDa (249aa) 28-40kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_059979

UniProt: Q9H2R5

Pathways: Komplementsystem