SFRP4 Protein (AA 19-346) (His tag)
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- Target Alle SFRP4 Proteine anzeigen
- SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 19-346
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses SFRP4 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- ADPVRGAPCE AVRIPMCRHM PWNITRMPNH LHHSTQENAI LAIEQYEELV DVNCSAVLRF FLCAMYAPIC TLEFLHDPIK PCKSVCQRAR DDCEPLMKMY NHSWPESLAC DELPVYDRGV CISPEAIVTD LPEDVKWIDI TPDMMVQERP LDVDCKRLSP DRCKCKKVKP TLATYLSKNY SYVIHAKIKA VQRSGCNEVT TVVDVKEIFK SSSPIPRTQV PLITNSSCQC PHILPHQDVL IMCYEWRSRM MLLENCLVEK WRDQLSKRSI QWEERLQEQR RTVQDKKKTA GRTSRSNPPK PKGKPPAPKP ASPKKNIKTR SAQKRTNPKR VHHHHHH
- Reinheit
- > 90 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product SFRP4 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))
- Andere Bezeichnung
- SFRP4 (SFRP4 Produkte)
- Synonyme
- SFRP4 Protein, FRP-4 Protein, FRPHE Protein, sFRP-4 Protein, secreted frizzled related protein 4 Protein, secreted frizzled-related protein 4 Protein, SFRP4 Protein, Sfrp4 Protein
- Hintergrund
- SFRP4, also known as secreted frizzled-related protein4, is a family of vertebrate proteins which contain homology to the ligand-binding domain of the Frizzled family of transmembrane receptors. It is expressed in brain, kidney, lung, ovary, prostate, mammary gland and endometrium. This protein act as soluble modulators of Wnt signaling, counteracting Wnt-induced effects at high concentrations and promoting them at lower concentrations. It is able to bind Wnt proteins and Frizzled receptors in the extracellular compartment. Recombinant human SFRP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 38.9kDa (337aa) 40-57KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_003005
- UniProt
- Q6FHJ7
- Pathways
- WNT Signalweg
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