LY9 Protein (AA 48-454) (His tag)

Produktnummer ABIN6387850

Produktdetails

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Protein-Typ: Recombinant

Proteineigenschaft: AA 48-454

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses LY9 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADLKDSAPTV VSGILGGSVT LPLNISVDTE IENVIWIGPK NALAFARPKE NVTIMVKSYL GRLDITKWSY SLCISNLTLN DAGSYKAQIN QRNFEVTTEE EFTLFVYEQL QEPQVTMKSV KVSENFSCNI TLMCSVKGAE KSVLYSWTPR EPHASESNGG SILTVSRTPC DPDLPYICTA QNPVSQRSSL PVHVGQFCTD PGASRGGTTG ETVVGVLGEP VTLPLALPAC RDTEKVVWLF NTSIISKERE EAATADPLIK SRDPYKNRVW VSSQDCSLKI SQLKIEDAGP YHAYVCSEAS SVTSMTHVTL LIYRRLRKPK ITWSLRHSED GICRISLTCS VEDGGNTVMY TWTPLQKEAV VSQGESHLNV SWRSSENHPN LTCTASNPVS RSSHQFLSEN ICSGPERNTK HHHHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Andere Bezeichnung: LY9 (CD229 Produkte)

Synonyme: LY9 Protein, CD229 Protein, SLAMF3 Protein, hly9 Protein, mLY9 Protein, AI893573 Protein, Lgp100 Protein, Ly-9 Protein, T100 Protein, lymphocyte antigen 9 Protein, LY9 Protein, Ly9 Protein

Hintergrund: LY9, as known as T-lymphocyte surface antigen Ly-9 isoform, is a type 1 transmembrane glycoprotein in the SLAM subgroup of the CD2 family. This protein consists of an extracellular domain with two lg-like V-set and two lg-like truncated C2-set domains. It is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between LY9 Molecules is mediated by the N-terminal lg-like domain. Also, this protein knockout mice show minimally impaired immune responses, suggesting functional redundancy with other molecules. Recombinant human LY9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 45.9kDa (416aa) 40-57kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_002339

UniProt: Q9HBG7

Pathways: BCR Signaling