GZMH Protein (AA 19-246) (His tag)

Produktnummer ABIN6387823

Produktdetails

Target: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-246

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses GZMH Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: EEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRLHH HHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Andere Bezeichnung: GZMH (GZMH Produkte)

Synonyme: GZMH Protein, CCP-X Protein, CGL-2 Protein, CSP-C Protein, CTLA1 Protein, CTSGL2 Protein, granzyme H Protein, LOC617313 Protein, GZMH Protein

Hintergrund: GZMH, as known as granzyme H isoform 1, is a member of the granzyme family of serine proteases found specifically in the granules of cytotoxic Tlymphocytes (CTL) and natural killer (NK) cells. The more abundant expression of this protein than granzyme B in NK cells suggests that granzyme H may complement the pro-apoptotic function of granzyme B in this cell type. Recombinant human GZMH, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 26.2kDa (234aa) 28-40kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_219491

UniProt: P20718